Colony-forming Abilityin vitroand Clonology of Colorectal Cancer

Role of Molecular Biomarkers in Colorectal Cancer

Colorectal cancer (CRC) is amongst the most widespread cancers and is a most common cause of cancer associated mortality universally. Since previous decades, it has been cleared that CRC develops owing to the buildup of a series of genetic and epigenetic changes in the normal colonic epithelium. Regardless of the current development in surgery and therapies, overall survival of end stage CRC pa...

Epigenetics in diagnosis of colorectal cancer

Colorectal cancer (CRC) is a third most common epithelial carcinoma. CRC is known to develop from the early precancerous lesion to full blown malignancy via definite phases due to cumulative mutations and aberrant methylation of number of genes. The use of serum biomarkers that is non-invasive to discriminate cancer patients from healthy persons will prove to be an important tool to improve the...

Colorectal Cancer and Prevention

   سرطان کولون و رکتوم یکی از انواع شایع - سابقه ابتلا به سرطان کولورکتال یا پولیپ های سرطانهاست که با وجود ایجاد مشکلات و عوارض متعدد در سلامتی انسانها، هنوز به طور جدی و کافی مورد توجه قرار نگرفته است. به طوریکه در سال ۲۰۰۴ بیش از ۱۳۰ هزار مورد جدید ابتلا به این بیماری در امریکا گزارش شده است. و طبق آمارهای انجمن سرطان آمریکا در سال ۲۰۰۲، از ۱۸۳۳۰۰ مورد ابتلا به سرطان کولورکتال۵۶ هزار مورد ب...

Broad Distribution of Colony-Forming Cells

Inhibition of Human Erythroid Colony-forming

We have previously reported that inhibition ofhuman CFU-erythroid (E) colony formation by tumor necrosis factor (TNF) is an indirect effect mediated by a soluble factor released from a fraction of marrow accessory cells which are predominantly stromal elements (Means, R. T., Jr., E. N. Dessypris, and S. B. Krantz. 1990. J. Clin. Invest. 86:538-541). Further studies reported here identify a medi...